Lily and Yuh Nung Jan
نویسنده
چکیده
Lily and Yuh Nung Jan's collaboration started with the identification of Shaker as the first known potassium channel gene and has flourished to produce over 100 former students and postdocs who are now leading their own research groups. In an interview with Neuron, they reflect on their scientific discoveries, serendipity in science, and the value of curiosity-driven basic research.
منابع مشابه
Evidence that direct binding of Gβγ to the GIRK1 G protein-gated inwardly rectifying K+ channel is important for channel activation
Chou-Long Huang,* t Paul A. Slesinger,* Patrick J. Casey,t Yuh Nung Jan,* and Lily Y. Jan* *Howard Hughes Medical Institute Department of Physiology Department of Biochemistry University of California San Francisco, California 94143-0724 tDivision of Nephrology Department of Medicine University of California San Francisco, California 94143-0532 1:Department of Molecular Cancer Biology Departmen...
متن کاملElectrostatic interactions in the channel cavity as an important determinant of potassium channel selectivity -- Bichet et al. 103 (39): 14355 Data Supplement - HTML Page - index.htslp -- Proceedings of the National Academy of Sciences
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متن کاملProfile of Lily and Yuh Nung Jan, winners of the 2017 Vilcek Prize in Biomedical Science.
The 2017 Vilcek Prize in Biomedical Science has been awarded to Lily Y. Jan and Yuh Nung Jan, professors in the department of physiology at the University of California, San Francisco (UCSF), and Howard Hughes Medical Institute Investigators. The Jans are being recognized for demonstrating how ion channels contribute to neuronal signaling and how neurons acquire their cell fates and morphologie...
متن کاملQ & A
Yuh-Nung Jan is at the University of California, San Francisco (UCSF). He studied Physics as an undergraduate at National Taiwan University. In 1968, he entered Caltech as a graduate student in theoretical high-energy physics. Two years later, he switched to biology. After he completed his Ph.D. with Max Delbrück in 1974, he joined Seymour Benzer’s lab as a postdoctoral fellow. There he began w...
متن کاملProbing protein electrostatics with a synthetic fluorescent amino acid.
Electrostatics affect virtually all aspects of protein structure and activity and are particularly important in proteins whose primary function is to stabilize charge. Here we introduce a fluorescent amino acid, Aladan, which can probe the electrostatic character of a protein at multiple sites. Aladan is exceptionally sensitive to the polarity of its surroundings and can be incorporated site-se...
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ورودعنوان ژورنال:
- Neuron
دوره 92 شماره
صفحات -
تاریخ انتشار 2016